Forthcoming

Nature BiotechnologyForthcoming in Nature Biotechnology

Nature MethodsEffective genome editing with an enhanced ISDra2 TnpB system and deep learning-predicted ωRNAs

Nature CommunicationsPredicting base editing outcomes with an attention-based deep learning algorithm trained on high-throughput target library screens

Nature ProtocolsForthcoming in Nature Protocols

Nature ProtocolsSystematic pegRNA design with PRIDICT2.0 and ePRIDICT for efficient prime editing

ScienceProgrammable genome editing in human cells using RNA-guided bridge recombinases

Nature Biomedical EngineeringTreatment of a metabolic liver disease in mice with a transient prime editing approach

Nature Biomedical EngineeringSpatial profiling of gene editing by in situ sequencing in mice and macaques

Genome BiologyPredicting adenine base editing efficiencies in different cellular contexts by deep learning

Nature CommunicationsEnhancing prime editor activity by directed protein evolution in yeast

Nature Chemical BiologyContinuous directed evolution of a compact CjCas9 variant with broad PAM compatibility

eLifeMutant SF3B1 promotes malignancy in PDAC

Nature BiotechnologyPredicting prime editing efficiency and product purity by deep learning

Cell ReportsSF3B1 facilitates HIF1-signaling and promotes malignancy in pancreatic cancer

Nature CommunicationsLoss of Rnf31 and Vps4b sensitizes pancreatic cancer to T cell-mediated killing

Molecular Therapy - Nucleic AcidsReplacing the SpCas9 HNH domain by deaminases generates compact base editors with an alternative targeting scope

Biotechnology and BioengineeringReduced apoptosis in Chinese hamster ovary cells via optimized CRISPR interference

Biotechnology and BioengineeringmiRNA engineering of CHO cells facilitates production of difficult‐to‐express proteins and increases success in cell line development

OncotargetInvestigation on tissue specific effects of pro-apoptotic micro RNAs revealed miR-147b as a potential biomarker in ovarian cancer prognosis